PPT-Quantifying contributions of mutations and homologous reco

genomic diversity Sergei Maslov Department of Biosciences Brookhaven National Laboratory New York Bacterial genome evolution happens in cooperation with phages Variation between E coli strains. Erica, . Nao. , Christian and Justine. What are Homologous Structures? . Structures derived . from a common . ancestor or . same . evolutionary or . developmental . origin. May not perform . the same function but they share a common ancestral origin. . 19. th. . Dec. ember 2013. Simulation Steering Group. Meeting. Carl Gwilliam. Marie-Helene. . Genest. Validations 18/12/13: DC14 (1). 5 validation tasks for this week: . Several DC14 . simulation . Informational Essay. The contributions ships have made to different cultures and economies. Source #1. Transporting Treasure. “The Deliverance was part of a global trading network that connected the indigenous peoples of the New World – and the vast mineral resources of their homelands – with Europe.”. Derived traits. are newly evolved features, such as feathers, that do not appear in the fossils of common ancestors. .. Ancestral traits. are more primitive features, such as teeth and tails, that do appear in ancestral forms.. (5) . Webquest. Comparative anatomy. provides . evidence of evolution . because it shows that various organisms share a common ancestor.. http://. cyemae.wordpress.com. /evolution-of-man/. H. omologous structures. Point mutations. single base change . silent mutation. no amino acid change. redundancy in code. missense. change amino acid. Changes the final protien. nonsense. change to stop codon. Stopping prematurely . Given a mutation, identify its type. Predict how a mutation will affect a protein.. Mutations. Changes in genetic material (DNA). 2 main types of mutations. Point mutation- change in one or a few nucleotides (letters). The sequence of bases in DNA are like the letters of a coded message or even the letters of a simple alphabet. . If we change the sequence of the letters do we change the nature of the message?. That . Understand how they occur. Analyze the different types of mutations. Understand how mutations affect amino acid sequences and proteins. Objective. Central Dogma. DNA is transcribed into RNA, RNA is translated into proteins. Conditional mutations. Point mutations. In . point mutations . the sequence of the DNA has been altered at a single position. Where this change consists of replacing one nucleotide by another, it is known as a . Science. Learning intention. To understand the different types of mutations. . You will need. A pen and a piece of paper or a laptop to record your answers. . You may need the internet to search for answers. . R. ecombination. 2. . Site-Specific . R. ecombination. 3. DNA . Transposition. Homologous Recombination at the Molecular Level. DNA BREAKS ARE COMMON AND INITIATE RECOMBINATION. Recombination repair DNA breaks by retrieving sequence information from undamaged DNA. There are two basic types of mutations:. Gene mutations - mutations that produce changes in a single gene. Chromosomal mutations - mutations that produce changes in whole chromosomes. Gene mutations . mutation. Mutations. Actual Mutations . in fruit flies. What is a mutation?. A mutation is any change in a cell’s DNA. A mutation can occur in an individual gene. - results in a single changed protein.