PPT-Immune mechanisms implicated in the tolerance induction to food allergens in children

3 rd International Conference and Exhibition on Clinical amp Cellular Immunology September 29 October 01 2014 Baltimore USA Rafael Correa Rocha Laboratory of Immuneregulation. Webinar. Subject : Allergen Management. Tutor : Dr. K.N. Shashikanth. Date: 07. th. October 2013. 2. Allergen Management. Allergen are substances, usually proteins which are capable of inducing an allergic reaction. Food allergens are typically naturally-occurring proteins in foods or derivatives of them that cause abnormal immune responses. . Preparing and Serving Food Safety in School Kitchens. Ben Chapman, PhD. Katrina Levine, MPH, RD, LDN. May 28, 2015. What is a Food Allergy?. Immune system has a negative reaction to something in a food. Mark S. Anderson, MD, PhD. UCSF. Disclosures. Research support from Juno Therapeutics. Consultant for . Sanofi. 2. 3. Lecture outline. Principles of immune regulation . Self-tolerance; mechanisms of central and peripheral . Medical Director, PAS. PROBLEM – National Concern. 60 Million Americans suffer from allergies. 40% of children – 30% of adults. 90% of asthma is triggered by allergies. Allergies increased 50% since 1997. Module 1. Module Content. Definitions. Types and prevalence of food allergies in . the United . States. Types and prevalence of food allergies in foreign countries. Impact of food allergies. Definitions. Immune reactions against self antigens—autoimmunity—are an important cause of certain diseases in humans, estimated to affect at least 1% to 2% individuals. the mere presence of . autoantibodies. Abul K. Abbas. UCSF. FOCiS. 2. Lecture outline. Self-tolerance; central and peripheral tolerance. Inhibitory receptors of T cells . Regulatory T cells . 3. Immunological tolerance. Definition:. . unresponsiveness to an antigen induced by exposure of lymphocytes to that antigen; antigen-specific (unlike “immunosuppression”). Case Study . What Happened. June 2014, Clarksville, TN. 11-year-old Landon Wood was visiting relatives in Tennessee when they decided to take a trip to Publix. Landon wanted a wrapped chocolate cookie for his treat. Dr. C Macaulay. Dr. C . Lemer. Dr. R Bhatt. Background. Food allergy may be confused with food intolerance. Food . allergy can be classified into . IgE. -mediated and non-. IgE. -mediated reactions. . immunological tolerance. Immunological . tolerance is a state of unresponsiveness to a particular antigen to which a person has been exposed earlier. .. . . The important aspect of tolerance is the self-tolerance, which prevents the body to mount immune response against self-antigens. Immunological unresponsiveness to self is referred to as . tolerance. or . self-tolerance. Very important to human health. How is this achieved?. -cells with receptors for self-antigens are destroyed in the thymus or bone marrow (central tolerance). iTrain. . Simple Lesson Plan . Introduction . Trainer and Participants’. Introductions. Welcome!. Do you have any children in your CACFP center with food allergies? What foods are they allergic to?. By . Dereick. Rushton. Hospitality and Catering Manager . Allergens. Short Video. Here is a short video about Allergens by the Food Standards Agency: . Why do we need to know about Allergens?. Allergic reactions can make people very ill and can sometimes lead to death. . Ben Chapman, PhD. Katrina Levine, MPH, RD, LDN. May 28, 2015. What is a Food Allergy?. Immune system has a negative reaction to something in a food. Something in the food causes the immune system to produce antibodies (.