PPT-17.6 Genetic Mutations

If the enzyme that converts tyrosine to melanin is defective no melanin is produced and a genetic disease known as albinism results A peacock with albinism does not produce the melanin needed to make the bright colors of its feathers. Changes in . DNA. that affect genetic information. Gene Mutations. Point Mutations – changes . in one or a few. nucleotides. Substitution. THE FAT CAT ATE THE RAT. THE FAT HAT ATE THE RAT. Insertion. Elie Traer. September 13, 2012. Outline. Genetic tests and methodology. Cytogenetics. , i.e. large chromosomal abnormalities. FISH, smaller chromosomal changes. Genetic mutations. AML. Evolution of genetic tests in diagnosis and prognosis. Mutation. Permanent change in the genetic material of an organism. All mutations in gametes are inheritable because they are copied during DNA replication. Somatic cell mutations occur in body cells. eyes, what . frequency of the population . is hybrid for brown eyes? Homozygous for brown eyes. ?. 2. . How . does sexual . reproduction . produce variation. ?. 3. Why are point/substitution mutations also known as silent mutations?. I. Wednesday . 3:30-4:20. p.m. Noland 342. II. Friday 1:20-2:10 p.m. Noland 539. Examples: Adaptation or not?. After high altitude training athletes have increased number of red blood cells (RBC). Nobody’s perfect all the time . About 1/10 billion base pairs end up with a error or mutation . Mutation: Mistake in DNA replication or an environmental effect that . results. in a change to the nitrogenous bases in DNA or RNA. . http://io9.gizmodo.com/10-unusual-genetic-mutations-in-humans-470843733. Unharmful. Mutations. Mila . Kunis. has complete . heterochromia. . Kate Bosworth has . sectoral. . heterochromia. . Angelina Jolie has central . Nobody’s perfect all the time . About 1/10 billion base pairs end up with a error or mutation . Mutation: Mistake in DNA replication or an environmental effect that . results. in a change to the nitrogenous bases in DNA or RNA. . M. istakes made in the DNA sequencing. They can have a range of effects.. They can affect the genetic information that is passed to offspring.. Cells have evolved various methods to deal with them. . The sequence of bases in DNA are like the letters of a coded message or even the letters of a simple alphabet. . If we change the sequence of the letters do we change the nature of the message?. That . Unit 8: Protein Synthesis . 6A: Identify components of DNA, identify how information for specifying the traits of an organism is carried in the DNA, and examine scientific explanations for the origin of DNA.. haematological. malignancies. Ass.Prof.Abeer. . Anwer. Ahmed. The . aetiology. of . haemopoietic. malignancy. Cancer . results from the accumulation of genetic mutations. within a cell and the number present varies widely from over. KEY CONCEPT:. . Mutations. are changes in genetic material.. VOCABULARY:. Mutation, point mutation, . frameshift. mutation, polyploidy. Mutations – extension from gene expression. . Changes in genotype. Learning Goal . Identify the type of change in DNA for a point mutation, a deletion mutation, and an insertion mutation. . Genetic Mutation. A. . mutation. is a change in the nucleotide sequence of DNA..