PPT-The Impact of Mutations Edited by:

Jessica Hawley Compiled By C Kohn Waterford WI Objectives Identify and analyze impacts of mutation Interpret impacts of mutation Analyze genetic information to determine mutations Work on SAE Record Books. Types . of Mutations | . Effects . of . Mutations. Learning Objectives. Identify different changes to DNA within both genes and chromosomes. Evaluate effects of changes to DNA on proteins produced and organisms’ overall survival. What Are Mutations?. Mutation: . Changes . in the nucleotide sequence of . DNA. Mutagen: . A physical or chemical agent that changes DNA. Mutation May . occur . in:. somatic cells (body cells): . will not be . Bases:. A, T, C, G. Codons:. Genes:. Chromosome:. DNA. Words. Chapters. Book. Not passed on to offspring. Can be passed on to offspring. M. ito. sis. M. eio. sis. Mutations. in Cell Division. A single gene. Mutations are changes in the genetic material. . Mutations may be genetic mutations or chromosomal mutations.. Genetic Mutations occur in the “code” on DNA or mRNA. Mistakes in . copying the DNA :. By: Kathryn Burrow. Edited Photo. Changed contrast and brightened photo. . Removed blemishes. . Removed lines by both of our eyes. . Added a Gaussian Blur to background. . Whitened teeth using paint bucket and changing the opacity. . P Ferguson, L . Quek. , M . Metzner. , I Ahmed, C Garnett, S Jeffries, K . Piechocki. , R Danby, M . Raghavan. , A . Peniket. , M Griffiths, A Bacon, J Ward, K Wheatley, P Vyas, C Craddock. Introduction. >2500 cancer genomes: Overall . functional . impact. Slides freely . downloadable . from . Lectures.GersteinLab.org. . & “tweetable” . (via . @. markgerstein. ). . See last slide . for more info.. What happens if there is a mistake (. mutation. ). in the DNA code?. Possibly proteins won’t be made or are made improperly.. If the mutations occur in the gametes, the offspring’s DNA will be affected positively, negatively, or neutrally.. http://io9.gizmodo.com/10-unusual-genetic-mutations-in-humans-470843733. Unharmful. Mutations. Mila . Kunis. has complete . heterochromia. . Kate Bosworth has . sectoral. . heterochromia. . Angelina Jolie has central . Understand how they occur. Analyze the different types of mutations. Understand how mutations affect amino acid sequences and proteins. Objective. Central Dogma. DNA is transcribed into RNA, RNA is translated into proteins. Small-scale mutations. Missense mutations. Nonsense mutations. Silent mutations. Frameshift mutations. Large scale mutations. Causes. Mutagens. The results of mutation. Mutations. Genetic mutations are changes in the DNA sequence, caused by various mechanisms.. AACR Annual Meeting 2012. Major Symposium: Designing Rational Combination Therapy for Cancer. Josh Stuart, UC Santa Cruz. Apr 3, 2012. Disclosure. SAB for Five3 Genomics. Overview of pathway-guided approach. Science. Learning intention. To understand the different types of mutations. . You will need. A pen and a piece of paper or a laptop to record your answers. . You may need the internet to search for answers. . There are two basic types of mutations:. Gene mutations - mutations that produce changes in a single gene. Chromosomal mutations - mutations that produce changes in whole chromosomes. Gene mutations .