PPT-Signal Transduction Ebaa M

Alzayadneh PhD Integrative Physiology and Pharmacology 1 Introduction to Physiology 0501110 Spring 2013 Subject Lecture No Lecturer Pages in the 11 th edition textbook Pages in the 12. Decimation or downsampling reduces the sampling rate whereas expansion or upsampling fol lowed by interpolation increases the sampling rate Some applications of multirate signal processing are Upsampling ie increasing the sampling frequency before D (from Kimura, 1966). Electron micrograph of 3 OHCs. spiral ligament. modiolus. When the basilar membrane vibrates up and down in response to the sound wave, the hair cell cilia are displaced 1. st. in one direction then in the other; i.e., 1. Chapter 13, . Stryer. Short Course. Signal Transduction. Signal from exterior of cell must affect interior of cell. Through the membrane. Amplification of signal. Ability to turn off. A few pathways…. FOR THE INSULIN MIMETIC ACTIVITY OF NEOHESPERIDOSE. Taro Kimura. , . Eisuke. Kato, Jun Kawabata. Laboratory of Food Biochemistry, Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University,. VOCABULARY. directions: mark each term to indicate if you know it, are unsure, or don’t.. amplify . communication. deleterious elaborate. embryology evolution . fluid . mosaic model mechanism. Pratt & . Cornely. , Chapter 10. Terms for Signal Transduction. Ligand. Receptor. Transducer. Effector. Second messenger. Target proteins/DNA. Ligands. Hormones vs Local mediators. Polar (insulin) vs nonpolar (steroidal hormone). Which of the following gives a correct and broadest description of signal transduction pathways?. binding of a signal molecule to a cell protein. catalysis mediated by an enzyme. sequence of changes in a series of molecules resulting in a response. Pratt & . Cornely. , Chapter 10. Terms for Signal Transduction. Ligand (first messenger). Receptor (transducer). Primary Effector. Second . messenger. Second effector, etc.. Target proteins/DNA. Ligands. Believed to have evolved in prokaryotes and single-celled eukaryotes. Single-celled organisms. Bacteria use communication in quorum sensing. Short distance communication using local regulators. Secrete . Dr. Kevin Ahern. EGFR Signaling, Part 1. Epidermal Growth Factor Receptor (EGFR). EGFR Dimer. Autophosphorylated. Tyrosines in . Cytoplasmic Domain. Signaling Complex. Assembled on . Phosphotyrosines. LO 3.36: The student is able to describe a model that expresses the key elements of signal transduction pathways by which a signal is converted to a cellular response. SP 1.5: The student can re-express key elements of natural phenomena across multiple representations in the domain. Z. Huang, Y. Chu, B. Cunha, and J. Hahn, transduction can alter cellular response.. SP 1.5. : The student can . reexpress. key elements of natural phenomena across representations in the Domain . Explanation. : A signal transduction pathway is where signal transduction occurs. Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. Receptor then causes a chain of event with in the cell, causing a cellular response. Signal transduction pathways can be altered. Signal transduction pathways can be blocked by the use of drugs such as antihistamines. Also signal transduction pathways being blocked can act as a preventative against diseases. A more specific impact of drugs altering cellular response is antihistamines. This changing signal transduction is how the antihistamines block transduction by blocking the histamine that is released by the cells immune system. When a foreign antigen binds to the . Learning Objectives. Learn the general structure and properties of hormones.. Know the differences between Hormones, Neurotransmitters & enzymes. 3. . Understand . the general properties of signaling molecules (ligands), cell-surface receptors, & intracellular signal transduction components..