PPT-Drug Absorption and Distribution

Alfred L George Jr MD Department of Pharmacology algeorgenorthwesternedu Drug Absorption Absorption refers to the transfer of a drug from its site of administration to the systemic circulation. Absorption and distribution in dicate the passage of the drug molecules from the administration site to the blood and the passage of drug molecules from blood to tis sues respectively Drug elimination may oc cur through biotrasformation and by the p A SEMINAR ON. . by. . V. Sandeep Kumar. . M.Pharmacy, I Sem.. Department of Pharmaceutics. University College Of Pharmaceutical Sciences. Natalie . Craythorne. 27. th. September. . 2013. Aims for today. To know what a drug is and how they are classified. To understand where drugs come from. Be able to explain the “lock and key” and induced fit hypotheses. . Gastrointestinal and Hepatic Systems. . Regulation of Drug Transport, Absorption, Distribution, Excretion and Metabolism. Dennis Paul, Ph.D.. Department of Pharmacology. 504-568-4740. rwainf@lsuhsc.edu. Mental picture of . what’s happening . inside…. … really might help.. Drug action (effects). Proportional to concentration at site of action. Concentration predicts better than dose. General Rules. 2. Transdermal drug delivery systems (TDDSs) facilitate the passage of therapeutic quantities of drug substances through the skin and into the general circulation for their systemic effects. . In 1965, Stoughton first conceived of the . BW733. October 1, 2013. Pharmacokinetics . WebQuest. 1. http://. www.speedlighter.ca/2011/12/25/why-i-shoot-stills/courtney-craig-photo-by-michael-willems. /. Overview. Introduction. Absorption. IV, . Dr. Jwan Mohammed. Oral route . Parenteral route. Intravenous. Intramuscular. Subcutaneous. Transdermal route. Rectal route . Pulmonary route . Oral route of administration. The oral route of administration is the most convenient route for drug administration because of low production cost, better suitability for self administration, higher level of patient safety and better patient . Lectures. Drug Mechanisms. Receptor Interactions. Pharmacokinetics. Pharm definitions and drug selectivity. Drug= A chemical substance that interacts with a biological substance to produce a physiological effect. Alfred L. George, Jr., M.D.. Department of Pharmacology. al.george@northwestern.edu. Drug Absorption. Absorption refers to the transfer of a drug from its site of administration to the systemic circulation.. . Regulation of Drug Transport, Absorption, Distribution, Excretion and Metabolism. Dennis Paul, Ph.D.. Department of Pharmacology. 504-568-4740. rwainf@lsuhsc.edu. Principles of Pharmacology. Common processes and mechanisms whereby: . Absorption of drugs. Definitions –. . Absorption of drugs can be defined as – . a process of movement of drug from the site of administration to site of measurement i.e. systemic circulation, in it’s unchanged form.. P’kinetics. Vd. . Shweta . yaragatti. Asst Professor Dept Of Dravyaguna. SMVVS RKM AMCH & RESEARCH CENTER . Email-. shwetayaragatti@gmail.com. Contents. Introduction. Pharmacokinetics. Absorption. UNIVERSITY . INSTITUTE OF PHARMACY. ,. CSJM University, . KANPUR. Absorption from the . gastrointestinal tract (GIT) is . governed by factors such as. :. S. urface area for absorption. Blood flow to the site of absorption.