Dr Geoff goodman Lecture 11 112216 Genes nature and nurture Introduction Genes work together with the environment to produce specific outcomes Distal factors that turn on or off genes Inequality ID: 630355
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Slide1
Developmental psychology
Dr. Geoff goodman
Lecture 11
11/22/16Slide2
Genes, nature, and nurture
Introduction
Genes work together with the environment to produce specific outcomes
Distal factors that turn on or off genesInequalityRacismSocioeconomic status Proximal factors that turn on or off genesParental monitoringCaregiver sensitivityMaltreatment (abuse or neglect)Moderational model: Low parenting monitoring x genetic predisposition adolescent smoking behaviorGenetic variation or allele can predict whether men marry or cohabitate – involved with vasopressin productionSlide3
Introduction cont.Epigenetics – environmental experiences can turn on or off certain genes
Stressful family situations might inhibit the expression of genes that protect against asthma
Dysfunctional family might turn on genes responsible for development of schizophrenia
Short version of 5ht gene involved in transporting serotonin is associated with depression, anxiety, and behavioral problems only when children experienced adversity Tph2 gene – implicated in development of adhd, panic disorder, bipolar disorder, suicidal behavior only when childhood adversity is present Monoamine oxidase (maoa) gene – implicated in violent or antisocial behavior only when child maltreatment is present Short version of drd4 gene – implicated in novelty seeking, adhd, and disorganized (d) attachment only when child has had traumatic, frightening parentingDrd2 gene – implicated in dopamine production Slide4
Introduction cont.Treatment implications
Higher doses of psychostimulant needed for adhd children with long version of drd4 gene
Parenting intervention more successful for adhd children with long version of drd4 gene
Purpose of these genetic variations – allows person to survive and thrive in a variety of environments Novelty-seeking genetic expression might aid in finding new territories (maasai In Kenya and Tanzania) Some children are more susceptible to rearing influences than others (belsky) Slide5
Genes affect behaviors in self and othersGenes can affect patterns of parenting
Short allele of 5ht gene
less sensitive parenting when parents have low social support or marital harmony
Twins separated at birth have demonstrated their influence on maternal warmth and marital harmony Nonshared environment – every child’s home life is unique because he or she is treated differently from siblingsSibling barricade – if one child is treated harshly, the sibling is protected (alternative explanation – splitting) 30% of mother’s hostile behavior is attributable to infant temperament Children of antisocial biological parents tend to have harsher, more inconsistent adoptive parents Slide6
Genes are not everything
Presumably genetic traits such as iq can change with environmental change
Romanian orphans can form attachments depending on age of adoption
Children are more likely to become depressed if the mother but not the father is depressed, regardless of the children’s genetic predisposition to depressionGenetics can have little to do with attachment quality, but Irritable temperament x low maternal support c attachmentShort version of drd4 gene x frightening parenting d attachment
Summary
Environment (e.g., maltreatment) might affect genes at the molecular level permanently
Epigenetics reflects changes in genetic expression, but a degree of plasticity still exists just in case environment changes later onSlide7
Conclusions: earlier experience and its longer-term consequences
Introduction
How much continuity is inevitable from early life?
How much change is possible as time goes on?Cascade of effects at various levels of analysisIndividualFamilyNeighborhoodSociety and cultureAttachment and the effects of earlier experiencesAttachment quality at one year is not often predictive of later developmental outcomes But it can start the ball rolling
Mediational model:
anxious-resistant
attachment
poor peer relationships depression
Poor peer relationships is the mediator
Internal working models exert a wide-reaching influence and reflect both current and earlier experiences Slide8
Attachment and the effects of earlier experiences cont.Changes in caregiver sensitivity and mind-mindedness can
supercede
the quality of internal working model and produce positive developmental outcomes in children Resilient children are more likely to overcome adversity but seem to suffer more from psychosomatic symptoms than children who did not face adversity Under stressful conditions, children still bear the scars of the adversity they facedSecure attachment predicts developmental outcomes when there is continuity in caregiver sensitivity and mind-mindedness Developmental trajectories model – attachment quality sets the table for future experiences, which in turn impact developmental outcomesSlide9
Childhood trauma and lack of good experiencesFoster care due to abuse or neglect
50% have mental health difficulties
Poor educational attainment
Higher risk of imprisonment – 25% of inmates had been in foster care Cumulative risk = higher likelihood of poor outcomes Five or more risk factors – 36 times more likely to be expelled from schoolFive risk factors could be 1) substance abuse2) domestic violence3) unemployment4) disability5) poor housingSlide10
What change is possible?
Trauma produces
chaotic
, incoherent thinking, particularly when stressedCaregivers cannot be trusted to provideOrderRoutineSafe boundariesThree months after adoption, changes can be observed in narratives prompted by story stemsOld worldviews often coexist with new worldviewsOld internal working models get activated during times of stress (neural pathways of least resistance under threat) – psychoanalysts used to describe this phenomenon as “regression” Children of adoptive parents classified as secure on the aai had the best outcomesInfants placed within first year adjust to new relationship patterns with adoptive caregivers
These infants are classified as secure if their adoptive parents are
similarly classified
In preschool, these children tell more coherent stories, reflecting
more benign representational worldsSlide11
What change is
possible?
cont.
Early interventions have enduring effectsChildren with adhd – less risk of psychoactive drug use Anorexia nervosa – less risk of mortalityAutism spectrum disorder – early speech and language intervention produces milder outcomesProblems with translating experimental interventions into clinical practiceEnthusiasm of intervention developer – related to outcome Comorbidity in the real world makes treatment difficultPatients’ awareness of the placebo condition artificially inflates findings in randomized controlled trials (Rcts) Slide12
What change is
possible?
cont.
Treatment effectiveness Therapeutic alliance (task, goal, bond) predicts positive treatment outcomes better than treatment model Outcomes also linked to therapist skill, not likability Some characteristics of the good therapist (common factors)Establishment of therapeutic allianceConsistency Hopes and expectations of improvementAdherence to treatment model (but not too much)Ability to repair treatment ruptures Intervention can take place at different ages and at different levels
Child
Parents
School system
Neighborhood and community
Society (political level)
For example, therapy to treat a mother’s depression results in improved outcomes for her child compared to the child of an untreated mother (indirect treatment)Slide13
ConclusionsSociological trends
Wider income gap is directly proportional to mental health problems at the lowest and highest extremes
Lower levels of community trust
Weaker community life and social support systemsCommunities become violentFamilies break upOutcomes worsen Moderational model: Maternal depression x economic deprivation impaired cognitive and emotional development in childrenWe need to account for both proximal and distal effects on children’s developmentWe Need to consider bidirectionality of causalityParents affect children and Children affect parentsBidirectionality holds true in child psychotherapy
between therapist and patient (goodman)Slide14
Conclusions cont.Single
best
predictor of resilience – lovability (think
carlyn—photo and video)Is it temperament?Is it sensitive, mind-minded caregiving?Is it economic and political stability? An individual enters every new situation bound by history and prior expectations but also open to new experiences and opportunities if he or she can set aside historical precedent Slide15
Mediational and moderational models
Moderational model
Iv
1 + iv2 + [iv1 x iv2] dvIv1 and iv2 are typically not associated with Each otherDv is continuousiv2 = moderator
Iv
1
predicts the dv only when Iv2 is present
For example, maoa gene variation + maltreatment + maoa gene
variation x
maltreatment
antisocial behavior (dv)
mediational model
Iv
mv dv
Four conditions must be true (baron &
Kenny,
1986)
Iv and mv are significantly correlated
Iv and dv are significantly correlated
Mv and dv are significantly
correlated
In a hierarchical regression analysis, mv significantly predicts the dv, and the iv becomes nonsignificant: iv (not significant)
mv*
dvSlide16
mediational model cont.
dv is continuous
mv = mediator
Iv acts through mv to predict the dvFor example, C attachment poor peer relationships depression (dv)C attachment poor peer relationships (condition 1)C attachment depression (condition 2)Poor peer relationships depression (condition 3)With c attachment and poor peer relationships entered together as predictors, c attachment no longer significantly predicts depression (condition 4)
C attachment has passed the baton of influence to poor peer relationships, which
directly
influence
the manifestation of depression
Remember – iv, mv, and dv are variables, not constants