PPT-DEPOLARIZING NEUROMUSCULAR-BLOCKING DRUGS

Dr S Parthasarathy MD DA DNB MD Acu Dip Diab DCA Dip Software statistics PhD physiology IDRA but In 1942 was DTC Succinylcholine introduced by Thesleff and . Journal . Club presenters: Drs. Ricky Harika, Sharanya Nama, Tom Talamo, Julie DeVore, and Andrew Gentilin. Neuromuscular Blockade and Post-Operative Respiratory Complications. EBM Statistics. Jim Ibinson. . Laura Lorenz. Mark Fischer . Larvingo. Alston . History . Native South America tribes smeared . a paste made from . Chondrodendron. . tomentosum. . on . blow darts and arrowheads to improve chances of obtaining wild game. . (PNF). Objectives:. Describe a brief history of PNF.. Define PNF.. List the purposes of PNF.. Be able to apply PNF when working with patients.. Brief History of PNF . ¹. Mid-1940’s: Neurophysiologist Dr. Herman Kabat developed PNF to rehabilitate the muscles of polio patients. Dr. Kaukab Azim. Drug List. Neuromuscular. Blockers. Spasmolytic Drugs. Non-depolarizing. Blockers. Depolarizing. Blockers. Central. Peripheral. Tubocurarine. Succinylcholine. Baclofen. Dantrolene. Mivacurium. Neuromuscular Blockers. Prevent acetylcholine from activating nicotinic. M. Cause muscle relaxation (paralysis). No oral forms. Cannot cross . Blood-brain barrier . No impact on CNS (paralysis, not sedation). ACH is synthesized in the cholinergic neurons from choline and acetyl CoA then stored in synaptic vesicles then it will be release into synaptic gap to bind post synaptic receptors and lead to biological response.. Done by: Ahmad Al-. Masri. Quick . Cholinergic . review . acetylcholine(. ACH. ) is neurotransmitter of the parasympathetic nervous system.. ACH. is synthesized in the . cholinergic neurons . from choline and acetyl CoA then stored in synaptic vesicles then it will be release into synaptic gap to bind post synaptic . Source:. . Anesthesiology . 6 2015, Vol.122, 1201-. 1213. . . http. ://. anesthesiology.pubs.asahq.org. /. Article.aspx?articleid. =. 2278676. Authors: Duncan J. McLean, . M.B.Ch.B. .; Daniel Diaz-Gil, . 14/3/2020. 1. Learning Objectives 1. Cholinomimetics. • Cholinomimetics: explain how (a) directly acting and (b) indirectly acting cholinomimetic drugs produce their biological actions and state why the former are more selective in their actions. Lecture . 5. Dr. Amar AL-. M. usawi. MD, PhD. Synaptic plasticity:. . It is the changes in the synaptic functions as a result of the history of discharging at a synapse, i.e. synaptic conduction can be strengthened or weakened on the basic of past experience. . Neuromuscular blockade in Critical Care. Aim. . To provide guidance on the administration and monitoring of neuromuscular blockade in Critical Care. Scope. All adult patients in intensive care receiving continuous neuromuscular blockade. . of. . Muscle. . Relaxants. Centrally. . active. Baclofen. Benzodiazepines. :. Tetrazepam . Diazepam. Clonazepam. Thiocolchicoside. Mephenoxalone. Tizanidine. Guaifenesin. Orphenadrine. Peripherally. October 2019. Michelle Coady. Neuromuscular Transmission . Skeletal muscle fibers are innervated by large, myelinated nerves . Nerve fibers branch out to stimulate several hundred skeletal muscle fibers. Objectives:. . List the classification of antipsychotic drugs used in schizophrenia.. Describe briefly the mechanism of antipsychotic action of these drugs. . Describe the pharmacological actions of antipsychotic drugs. .