PPT-Gene Control of Eukaryote Development

Homeotic Genes Type of master gene that controls formation of specific body parts during development Antennapedia Expressed in the thorax causes legs to form Expressed in the head causes legs to form there also. Eukaryotic Gene Regulation. How are genes turned on & off . in eukaryotes?. How do cells with the same genes differentiate to perform completely different, specialized functions?. Evolution of gene regulation. What does the operon model attempt to explain?. the coordinated control of gene expression . in bacteria. bacterial resistance to antibiotics. how genes move between homologous regions of DNA. the mechanism of viral attachment to a host cell. hr. 2 from 3 (1 is compulsory). 1). Discuss the . regulation . of the . Hunchback . gene during Drosophila embryogenesis .  .  . 2) . Give examples of inducing centers that control gene expression and morphogenesis during development. Illustrate your answer with a description of an experiment that elucidates the type of control you have described. . Cellular Control – . homeobox. genes and apoptosis. Learning Outcomes. explain that the genes that control development of body plans are similar in plants, animals and fungi, with reference to . homeobox. Energy and nutrient cycles. Lindeman’s theory of . energetic ecologic . was . th. main trigger to initiate the international biological program (IBP) that run from 1964 to 1974 (European projects ended in the 80s). . Control in Division & Development. pp 217-228. Prokaryotes. 1965 Nobel Prize to Jacob & Monod for work on . lac. operon in . E. coli. Lactose is metabolized by 3 enzymes in . E. coli. Genes for these proteins are sequential. Biology Unit 04 Lesson 01. Prokaryotes – What are they?. Cells (usually single-celled) with no nucleus. Have no specialized organelles. Usually have: cell wall, cell membrane, ribosomes, genetic material, cytoplasm, and flagella or cilia. TUMOR SUPRESSOR PROTEINS. ATP. ENZYMES THAT CONTROL CELLULAR RESPIRATION. ADAPTIVE GENE PRODUCTS ARE ONLY REQUIRED UNDER CERTAIN CONDITIONS. GENES FOR PROTEIN DIGESTION ARE TURNED OFF WHEN THERE IS NO PROTEIN AVAILABLE. . 10.1 Between You and Eternity. Cancer is a multistep process in which cells grow and divide abnormally, disrupting physical and metabolic functions. More . than 200,000 new cases of breast cancer are diagnosed in the US each year – about 5,700 in women and men . REFERENCES 1 Friedman JR and Kaestner KH The Foxa family of transcription factors in development and metabolism 2006 Cell Mol Life Sci 63 2317-2328 2 Oliveri P Walton KD Davidson EH and McClay DR Repr REFERENCES 1 Friedman JR and Kaestner KH The Foxa family of transcription factors in development and metabolism 2006 Cell Mol Life Sci 63 2317-2328 2 Oliveri P Walton KD Davidson EH and McClay DR Repr John Parrish. Errors in Fertilization. Polyspermy - polyandry. Multiple sperm penetration. Invertebrates. excess sperm eliminated because sperm centriole contributes to first embryonic cleavage spindle. Controlling gene expression is often accomplished by controlling transcription initiation.. Regulatory proteins . bind to DNA to either block or stimulate transcription, depending on how they interact with RNA polymerase.. Acknowledgement. Centers for Disease Control and Prevention- Ethiopia (CDC-E). American Society for Clinical Pathology (ASCP). Addiss. Ababa University . University of Gondar. University of . Hawassa.