PPT-Amino Acid Degradation and Nitrogen Metabolism

Chapter 30 Stryer Short Course Overview Amino Acid Catabolism Nitrogen removal Urea Cycle Metabolism of carbon backbone Amino acid catabolism Amino acids from diet or protein turnover Salvaged for use in proteins or catabolized. Linda F. Bisson. Department of Viticulture and Enology. UC Davis. April 18, 2014. Nitrogen Composition of Grapes. Variety of nitrogenous compounds in grape juice. Nitrogen compounds vary by variety and with environmental conditions. Pratt and . Cornely. Chapter 18. Overview. Nitrogen assimilation. Amino acid biosynthesis. Nonessential aa. Essential aa. Nucleotide biosynthesis . Amino Acid . Catabolism. Urea Cycle. Juicy Steak Part 2. Stryer. Short Course, Chapter 31. Nitrogen fixation. Bacteria. Nitrogenase. Costly—16 ATP per N. 2. molecule. Assimilation into Amino Acids. In microorganisms/plants: assimilation of ammonia is key—synthesis of most amino acids. Nitrogen Metabolism. Nitrogen Forms in the Body. Nitrogen Balance Critical. Body Must Make and Break Down Amino Acids. Nitrogen Also Needed for Synthesis of. Nucleotides (ATP, GTP, CTP, UTP, dATP, dCTP, dGTP, dTTP). CATABOLISM. fig 18-1. fate of amino nitrogen in mammals. fig 18-2. metabolism of amino nitrogen in liver. fig 18-2. nitrogen removal molecules…. fig 18-2. metabolism of amino nitrogen in liver. pg 677. 1. . Overview. The catabolism of the amino acids involves:. Removal of α-amino groups. . Breakdown of the resulting carbon skeletons.. The resulting compounds will be used to form seven intermediate products: . . 1. Nitrogen Fixation. 2. Amino Acid Biosynthesis. Nitrogen. is an essential element found in . proteins. , . nucleic acids . and many other molecules. Biologically available nitrogen is scarce. Approximately 75% are reutilized.. The excess nitrogen forms urea.. Proteins represent 10-15 % of total energy supply.. Digestion and Absorption of Proteins.. The . α. -amino group of many amino acids is transferred to . UNIT IV:. Nitrogen Metabolism. Part . 3. Neonatal screening and diagnosis of PKU: . Early . diagnosis of phenylketonuria is important because the disease is treatable by dietary means. . Because of the lack of neonatal symptoms, laboratory testing for elevated blood levels of phenylalanine is mandatory for detection. . Peptide bond formation. : . α-carboxyl group of one amino acid (with side chain R1) forms a covalent peptide bond with α-amino group of another amino acid . ( . with the side chain R2) by removal of a molecule of water. The result is : Dipeptide ( i.e. Two amino acids linked by one peptide bond). By the same way, the dipeptide can then forms a second peptide bond with a third amino acid (with side chain R3) to give . VBC-607. Unit-1. P.G.. 6.11.2020. MAPLE SYRUP URINE DISEASE. Also known as Branched chain ketonuria. Partial or complete deficiency of branched-chain . α . keto acid dehydrogenase (a multienzyme complex associated with inner membrane of mitochondrion). Unit-1. P.G.. 25.09.2020. Oxidative Deamination . L-AA oxidase and D-AA oxidase act on L-AA and D-AA respectively and oxidatively removes NH. 3. from AA.. Glutamate formed by transamination reactions is deaminated to . KWWSVGRLRUJ316 3XEOLVKHGRQOLQHE\&DPEULGJH8QLYHUVLW\3UHVV in the studies are undertaken, mat (N. utritionally. . Essential & Nutritionally Non Essential Amino . Acids ). Lecture : 4. Dr. . Shaimaa. . Munther. Nutritionally Essential & Nutritionally Non Essential Amino Acids . Introduction: .