PPT-Genetic Polymorphism in Drug Metabolism – CYP450

Isoenzymes Presented by Lahari Paladugu PharmD 0910 Presented on February 7 2014 What is Genetic Polymorphism 1 The existence together of many forms of DNA sequences at . Understanding:. Metabolic pathways consist of chains and cycles of enzyme-catalysed reactions. Enzymes lower the activation energy of the chemical reactions that they catalyse. Enzyme inhibitors can be competitive or non-competitive. A. Metabolism. 1. Anabolism. A) synthesis reactions (building up). 2. Catabolism. A) lysis reactions (breaking down). B. Enzymes. 1. proteins that facilitate chemical reactions. Microbial Metabolism. MOVE Support . August 5, 2014. Glenna Stewart, MS RD LD. Energy Balance. Carbohydrate. . . Fat. Protein. Basal Metabolism. Physical Activity. Digestion, Absorption, & Processing Nutrients. METABOLISM OR BIOTRANSFORMATION . The conversion from one chemical form of a substance to another. . The term metabolism is commonly used probably because products of drug transformation are called . A. Metabolism. 1. Anabolism. A) synthesis reactions (building up). 2. Catabolism. A) lysis reactions (breaking down). B. Enzymes. 1. proteins that facilitate chemical reactions. Microbial Metabolism. Dr Anissa Atif Mirza. What is Metabolism?. Metabolism is a . network of metabolic /biochemical reactions.. Carried out in living cells.. In a. well organized, integrated and regulated manner.. Related to various biomolecules viz. Cellular Respiration. Chapters 8-10. Metabolism and Energy. Metabolism. Catabolism. Anabolism. Bioenergetics. Energy. Kinetic. Heat/Thermal. Light Energy. Potential. Chemical. Organisms are energy transformers!. We have touched on their metabolism.. Now we will wrap that up a bit by describing once you have digested carbohydrates, lipids, and proteins, what does your body do with it.. Metabolism. Metabolism:. Symposium. March . 31, 2016. Inborn Errors of Metabolism:. Metabolomics. Gerard T. Berry, MD. Professor of Pediatrics, Harvard Medical School. Director, Metabolism Program. , . Boston Children’s Hospital. Liver dysfunction and Drugs metabolism Dr V.Sebghatollahi Isfahan university of medical science Liver Functions: Metabolism – Carbohydrate, Fat & Protein Secretory – Bile acids, bile salts 2. Static Binding Vs. Dynamic Binding. 3. Binding. means associating a method definition with its invocation. It can be also called . early binding. Polymorphism that is resolved during compiler time is known as static polymorphism. Method overloading is an example of compile time polymorphism.. Joseph McGraw, Pharm.D., M.P.H., Ph.D.. Associate Professor of Pharmaceutical Sciences . CUW School of Pharmacy . President and Chief Scientific Officer . Persotype. DX LLC. Background. Ph.D.-Biopharmaceutical Sciences. RFLP. ). Fluorescence . in situ . Hybridization . (. FISH. ). Start C. odon Targeted . (. SCoT. ) P. olymorphisms. E. xpressed . S. equence . T. ag . (. EST. ). Random Amplified Polymorphic DNA (. RAPD. west. Prepared By:. Rakiaa. Michael Saeed. Supervised by:. Asst. Prof. Dr. . Gulzar. I. Ibrahim. . Introduction . However, the term . xenobiotics. is very often used in the context of pollutants such as dioxins and polychlorinated biphenyls and their effect on the biota, because .