PPT-Pharmacodynamics (cont.)

Graded Doseresponse Relationships Agonist drugs mimic the action of the original endogenous ligand for the receptor for example isoproterenol mimics norepinephrine on β1 receptors of the heart The magnitude of the drug effect depends on the drug concentration at the receptor site which in turn is determined by both the dose of drug administered and by the drugs pharmacokinetic profile such as rate of absorption distribution metabolism and elimination. 54 Cont act resistance to a thin semiconductor layer The contact between a metal contact and a thin conducting layer of semiconductor can be described with the resistive network shown in Figure 35 which is obtain (last updated . 2011-10-05). Aim. For high loadings/short lives (with respect to the number of load cycles), fatigue life calculations are generally strain-based.. The . aim of this presentation is to give a short introduction to . Joseph Francis Max . Perrella. And Kirk . McKeever. Mulligan. Contents. Title . Contents. Background: What is Yawning?. Background:. Why do we Yawn. Background:. Animal Yawning. Why is Yawning Contagious. Simplified. Basic Guidelines. To obtain the floor(right to speak). Stand when the person speaking has finished . State, Mr./Madam Chairman. You must be recognized by the chair before speaking . Standing while another has the floor is out of order . Martyrdom, Asceticism and Monasticism. 1. Martyrdom. According to Origen and Tertullian:. “ The life of the Christian ought to be a preparation for martyrdom”.. 2. Martyrdom, cont.. Origen differentiates between two types of martyrdom:. Principles of cavity preparation . Black’s classification. Class I cavity. All pit and fissure cavities. Occlusal surfaces of posterior teeth . Occlusal 2/3 of buccal and lingual surfaces of premolars & molars. Dr. Jennifer Patterson. Dr. Melissa Rowland . MidAmerican Psychological Institute, P.C.. Objectives. Define hoarding. Identify different types of hoarding. Causes of hoarding. How hoarding evolves. Treatment and prognosis. (last updated . 2011-10-11). Aim. For high loadings/short lives (with respect to the number of load cycles), fatigue life calculations are generally strain-based.. Since global plastic flow generally is not acceptable, we will focus attention on localized plastic flow at local stress raisers/stress concentrations. Having found the total cyclic strain range occurring there, we may then go on and calculate the expected life by e.g. Morrow’s equation.. “Theories on the Nature of the State”. 21. st. August, 2014. LECTURE No 6. The Nature of the State. This lecture will attempt to establish the following:. The Nature of the Socialist State. The Nature of the Welfare State. NICOTINE ADDICTION. U.S. Surgeon General’s Report. Cigarettes and other forms of tobacco are addicting.. Nicotine is the drug in tobacco that causes addiction.. The pharmacologic and behavioral processes that determine tobacco addiction are similar to those that determine addiction to drugs such as heroin and cocaine.. Management of NSTE-ACS Dr shahinlal ACS v/s Chronic stable angina Sudden onset of symptoms at rest/ minimal exertion At least lasting for 10 min unless treated promptly. Severe pain/ pressure/discomfort in chest Mycobacteria tuberculosis . DNA gyrase inhibitors . EMMANUEL MOYO. Treatment is lengthy and complex. Treatment for drug susceptible TB is 6 month course . - Isoniazid, Rifampicin, Ethambutol and Pyrazinamide. A further cohort . of rabbits received amikacin 3.33mg/kg q8h . i.v.. or 5mg/kg . i.v.. q8h in combination with meropenem 5mg/kg . s.c.. q8h. Although this had minimal additional effect on the total bacterial population, the emergence of a meropenem-resistant population was suppressed compared to monotherapy. Graded Dose-response . Relationships:. Agonist drugs mimic the action of the original endogenous ligand for the receptor (for example, isoproterenol mimics norepinephrine on β1 receptors of the heart). .