PPT-Drug Receptors &

Pharmacodynamics Seyed Ali Ziai Receptor Pharmacologic antagonists Macromolecular Nature of Drug Receptors Regulatory proteins Enzymes Transport proteins Structural proteins Receptor Effector Coupling. . DR NARENDRA KUMAR. . Pharmacodynamics. is the study of the biochemical and physiological effects of drugs and their mechanisms of action. . Simply stated, . pharmacodynamics. refers to the effects of a drug on the body.. Pharmacodynamics. Pharmacodynamics. The study of the biochemical and physiologic effects of drugs and the molecular mechanisms by which those effects are produced . The study of what drugs do to the body and how they do it . Department of Biochemistry. GITAM UNIVERSITY. India. Editorial Board Member. Journal . of Marine Science: Research & Development. Journal of Marine Science: Research & Development. ISSN: 2155-9910. A Selective Overview. Carl Rosow, M.D., Ph.D.. Disclosures. Consultant – Salix Pharmaceuticals. Topics for Today. Pharmacodynamics. Receptors, potency, efficacy. Agonists, antagonists. The dose response curve. Dr. SA . Ziai. Pharmacology. Pharmacology . can be defined as the study of substances that interact with living systems through chemical processes, especially by binding to regulatory molecules and activating or inhibiting normal body processes. . Receptor. A receptor is a protein molecule usually embedded within the cell membrane with part of its structure exposed on the outside of the cell.. The protein surface is a complicated shape containing hollows, ravines, and ridges.. Drug abuse . is . inappropriate. and usually . excessive. , . self-administration. of a . psychoactive . drug for . non-medical purposes.. Almost all abused drugs exert . their effects in the CNS . Alison Taylor. Heroin. H, Smack, Dope, Junk. Can be purchased as a . white powder – . “White China” . or a dark resin – . “Black Tar”. Opiates. . Derived from the opium poppy. Morphine: Used as a painkiller in hospitals. Dr N. K. . Kansal. Associate Professor. Basic principles. Medications – Can target the skin by either topical/ . intralesional. / systemic routes. I. ntralesional. administration – Additional option for very localized lesions . inappropriate. and usually . excessive. , . self-administration. of a . psychoactive . drug for . non-medical purposes.. Almost all abused drugs exert . their effects in the CNS . causing. euphoria or alter perception.. 1 Beta - blockers have been widely used in the management of angina, certain tachyarrhythmias and heart failure, as well as in hypertension . Examples Acebutolol Atenolol Bisoprolol Carvedilol Celip 1 Pharmacology Pharmacodynamics: How Drugs Work J K Aronson Contents 1 . The types of pharmacological actions of drugs 1.1 . Drug action via a direct effect on a receptor 1.2 . Short - term and long - Pharmacodynamics. D-R Interact.ions and Pharmacodynamics. Pharmacodynamics. . Describes the actions of drugs on the body and the influence of drug . concentration on the magnitude of the response. Antipsychotic drugs. 1. Dopamine- serotonin hypothesis of schizophrenia. 2. Classification of antipsychotic drugs. 3. Basic concepts about their receptors action. 4. Basic concepts about their related effects/ side effects and how to manage them.