PPT-24.9 Synthesis of Amino Acids

Plants and bacteria produce all of their amino acids using NH 4 and NO 3 Humans can synthesize 9 of the 20 amino acids found in their proteins Nonessential amino acids are synthesized in the body while essential amino acids must be obtained from diet. Identify and compare DNA and RNA.. Explain the three types of RNA.. Demonstrate understanding using codon and anticodon sequences.. Objectives. Protein Synthesis. Protein Synthesis. DNA contains . genes. Protein Synthesis. Protein Synthesis. DNA contains . genes. sequences . of nucleotide bases. These Genes code for . polypeptides (proteins). Proteins. are. used . to build cells and do much of the work inside cells. What to Know. What is the Metabolic Fate of Ammonium?. How is Escherichia coli Glutamine Synthetase regulated?. Understand general ways that organisms synthesize amino acids. Know the definition of essential versus nonessential amino acids. DR AMINA . BIOCHEMISTRY. All tissues have some capability for synthesis of:. The non-essential amino acids,. Amino acid remodeling, . and Conversion of non-amino acid carbon skeletons into amino acids and other derivatives that contain nitrogen. . 1. . Overview. The catabolism of the amino acids involves:. Removal of α-amino groups. . Breakdown of the resulting carbon skeletons.. The resulting compounds will be used to form seven intermediate products: . Richard D. Howells, PhD. Dental Biochemistry Lecture 24. 2. Learning Objectives. To describe the urea cycle and its fundamental role in the excretion of nitrogen.. To . distinguish between . glucogenic. . are organic molecules that are the building block of . . proteins. .. -There is 20 . α. -amino acids commonly found in . proteins. . ( . they . have a carboxyl group and an amino group . . . TO SPECIALIZED PRODUCTS. Lec. . Dr. . Shaimaa. . Munther. CONVERSION OF AMINO ACIDS TO SPECIALIZED PRODUCTS. In addition to serving as building blocks for proteins, amino acids are precursors of many nitrogen-containing compounds that have important physiologic functions.. (N. utritionally. . Essential & Nutritionally Non Essential Amino . Acids ). Lecture : 4. Dr. . Shaimaa. . Munther. Nutritionally Essential & Nutritionally Non Essential Amino Acids . Introduction: . codons.  that define specific amino acids. Many questions pertaining to this genetic code were posed in the late 1950's:. • How many RNA nucleotide bases designate a specific amino acid?. If separate groups of nucleotides, called . What are nucleic acid ?. Linear polymers of . nucleaotides.first. isolated by . Miescher. (. 1871). Each nucleotide consist of 3 components . 1. . purine. or . pyrimidine. . nucleobase. or Biosynthesis . Microorganisms . can obtain . energy. in many ways, much of this energy is used in biosynthesis or . anabolism. . During biosynthesis, . m.o. begins with . simple . precursors. , such . BSc 3. rd. year . AMINO ACIDS. C. lassification of amino acids . Classification according to nature of side chain. PREPARATION OF AMINO ACIDS. 1. Gabriel Phthalimide synthesis. 2. Strecker’s synthesis. Metabolic relationship of Amino Acids. Biosynthesis of Amino Acids. The carbon skeletons of many amino acids may be derived from metabolites in central pathways, allowing the biosynthesis of some, but not all, the amino acids in humans.