PPT-1 Metabolism of Amino Acids. Part II

Richard D Howells PhD Dental Biochemistry Lecture 24 2 Learning Objectives To describe the urea cycle and its fundamental role in the excretion of nitrogen To distinguish between glucogenic. Pratt and . Cornely. Chapter 18. Overview. Nitrogen assimilation. Amino acid biosynthesis. Nonessential aa. Essential aa. Nucleotide biosynthesis . Amino Acid . Catabolism. Urea Cycle. Juicy Steak Part 2. 18. /2014. Biochemistry I. Dr. Loren Williams. Proteinogenic Amino Acids. An amino acid contains . an amine group . a carboxylic acid group, . a side-chain (or R-group,. all attached to the same chiral carbon atom (the Cα). What to Know. What is the Metabolic Fate of Ammonium?. How is Escherichia coli Glutamine Synthetase regulated?. Understand general ways that organisms synthesize amino acids. Know the definition of essential versus nonessential amino acids. building blocks for protein synthesis. precursors of nucleotides and heme. source of energy. neurotransmitters. precursors of neurotransmitters and hormones. Outline of amino acid degradation. The liver is the major site of degradation for most amino acids, but muscle and kidney dominate the degradation of specific ones. 1. . Overview. The catabolism of the amino acids involves:. Removal of α-amino groups. . Breakdown of the resulting carbon skeletons.. The resulting compounds will be used to form seven intermediate products: . . 1. Nitrogen Fixation. 2. Amino Acid Biosynthesis. Nitrogen. is an essential element found in . proteins. , . nucleic acids . and many other molecules. Biologically available nitrogen is scarce. . are organic molecules that are the building block of . . proteins. .. -There is 20 . α. -amino acids commonly found in . proteins. . ( . they . have a carboxyl group and an amino group . . . main role of amino acids . is in the. . synthesis of structural and functional proteins. .. . The non-essential amino acids are either derived from the. . diet or synthesized in the body. .. . The . Intermediary Metabolism. OR. Interrelationship Between Various Metabolic . Pathways. OR. Interdependence Of Metabolic Pathways. To Better Understand Metabolism Of Various Biomolecules . Metabolism of each . VBC-607. Unit-1. P.G.. 6.11.2020. MAPLE SYRUP URINE DISEASE. Also known as Branched chain ketonuria. Partial or complete deficiency of branched-chain . α . keto acid dehydrogenase (a multienzyme complex associated with inner membrane of mitochondrion). Protein. Builds and repairs body tissue. Provides some energy. There are 4 calories per gram of protein. Protein. Composed of chains of amino acids. Common Amino Acids. Alanine. Glycine. Isoleucine. Leucine. BC 2.5 Microbiology and Genetics 12 2 6 85 BC 2.6 Quantitative Analysis and Molecular Biology 12 2 6 85 BC 2.7 Viva-Voce -- 1 25 ----- Total marks Acids (1992) 2:25-67 diagnosis of (inherited) amino acid metabolism or transport disorders W. Blom and J. G. M. Huijmans Laboratory, Department of of amino acid metabolism or transport are most cle (N. utritionally. . Essential & Nutritionally Non Essential Amino . Acids ). Lecture : 4. Dr. . Shaimaa. . Munther. Nutritionally Essential & Nutritionally Non Essential Amino Acids . Introduction: .