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Catalog code tlrladphVersion 21F08ED Catalog code tlrladphVersion 21F08ED

Catalog code tlrladphVersion 21F08ED - PDF document

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Uploaded On 2021-09-02

Catalog code tlrladphVersion 21F08ED - PPT Presentation

CHEMICAL PROPERTIESFormula CMolecular weight 72021 gmol stable formSolubility 10 mgml HO and vortex until Prepare aliquots and store at 20Working concentration range Activation of the ALPK1TIFA si ID: 875029

signaling tifa heptose product tifa signaling product heptose adp stable alpk1 store aliquots x00660069 rmed bacterial pathway biosynthesis activation

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1 Catalog code: tlrl-adphVersion 21F08-ED
Catalog code: tlrl-adphVersion 21F08-ED CHEMICAL PROPERTIESFormula: CMolecular weight: 720.21 g/mol (stable form)Solubility: 10 mg/ml HO and vortex until Prepare aliquots and store at -20Working concentration range: Activation of the ALPK1-TIFA signaling axis by ADP-Heptose Below is a protocol for using InvivoGen’s HEK-Blue™ Null1-v cells,  KO-TIFA KO-ALPK1 to study the activation of the ALPK1-TIFA signaling pathway in 69 ADP-Heptose is provided as a dried powder and shipped at room temperature. Upon receipt, store product at -20°C. prepare aliquots and store °C. Resuspended product is stable for up to 3 months when 95% (UHPLC)TIFA signaling pathwayhas been con�rmed Absence of bacterial contamination (i.e. endotoxins) has been con�rmed using a kinetic chromogenic LAL assay, with an endotoxin level /mg.PRODUCT DESCRIPTIONADP-Heptose is an intermediary sugar in the biosynthesis of lipopolysaccharide (LPS), an essential component of the Gram negative bacterial outer membrane. It is generated by a multi-step biosynthesis pathway, in which the final step is the interconversion between two isomers, ADP-D-glycero- O HO HO HO O HO P O O O P O O OH NN NN NH2 O OH OH OH Et3NH Stable form