PPT-Figure 3 Figure 3. Detection of WU polyomavirus viral protein 1 in CD68-positive cells

Siebrasse EA Nguyen NL Willby MJ Erdman DD Menegus M Wang D Multiorgan WU Polyomavirus Infection in Bone Marrow Transplant Recipient Emerg Infect Dis 20162212431 httpsdoiorg103201eid2201151384. CSE 576. Face detection. State-of-the-art face detection demo. (Courtesy . Boris . Babenko. ). Face detection and recognition. Detection. Recognition. “Sally”. Face detection. Where are the faces? . Schematic. of . picornavirus. . genome. . organization. . The positive-. strand. RNA has the viral . protein. . VPg. . covalently. . linked. to the 5′ end of the . genome. . . Both. the 5′ and 3′ . Council of State and Territorial Epidemiologists Annual Conference. June 4, 2012. Omaha, Nebraska. Tom Jaenicke, MPH, MBA, MES. Washington State Department of Health. Tom.Jaenicke@doh.wa.gov. Outline for today. 1957. Isaacs and . Lindenmann. . Did an experiment using chicken cell cultures. Found a substance that interfered with viral replication and was therefore named interferon. What are . Interferons. ?. State-of-the-art face detection demo. (Courtesy . Boris . Babenko. ). Face detection and recognition. Detection. Recognition. “Sally”. Face detection. Where are the faces? . Face Detection. What kind of features?. The canine meningoencephalitides of unknown etiology (MUE). GME,NME,NLE. Histopathologic lesions are similar to those present in human viral meningoencephalitis. PCR method has demonstrated that 50-70% of human meningoencephalitides are caused by CNS viral infections.. . Understanding microscopic features and laboratory techniques for diagnosis of causative viral pathogens.. Intended learning objectives. Meningitis. . Causes of viral meningitis (aseptic meningitis):. July 2010. Polyomaviruses. Small DS DNA viruses. Cause “poly” “. omas. ”. Non-human . polyomaviruses. :. Murine. K . virus, discovered 1952 [1]. Simian virus 40 (SV40. ). Human . polyomaviruses. Viruses are very small – smaller than the smallest cell.. They are usually surrounded by a capsid of proteins.. For replication, viruses rely on their host cells . ie. ., the cells they infect.. Most viruses exhibit a limited host range- they typically infect only specific types of cells of one host species.. Introduction:. Viral infections of plants can cause necrosis, hypoplasia . or . hyperplasia and these effects can lead to symptoms such as. Growth retardation . Distortion. Mosaic patterning of leaves. Viral Replication. Viruses multiply only in living cells (As viruses are obligate intracellular pathogens they cannot replicate without the machinery and metabolism of a host . cell). . . The . host cell must provide the energy and synthetic machinery and the low-molecular-weight precursors for the synthesis of viral proteins and nucleic acids. . van der Meijden E, Wunderink HF, van der Blij-de Brouwer CS, Zaaijer HL, Rotmans JI, Bavinck J, et al. Human Polyomavirus 9 Infection in Kidney Transplant Patients. Emerg Infect Dis. 2014;20(6):991-999. https://doi.org/10.3201/eid2006.140055. Albariño CG, Foltzer M, Towner JS, Rowe LA, Campbell S, Jaramillo CM, et al. Novel Paramyxovirus Associated with Severe Acute Febrile Disease, South Sudan and Uganda, 2012. Emerg Infect Dis. 2014;20(2):211-216. https://doi.org/10.3201/eid2002.131620. Bai Y, Du Z, Wang L, Lau E, Fung I, Holme P, et al. Public Health Impact of Paxlovid as Treatment for COVID-19, United States. Emerg Infect Dis. 2024;30(2):262-269. https://doi.org/10.3201/eid3002.230835.