PPT-Btk inhibition in Mantle cell Lymphoma & CLL

Simon Rule Professor of Clinical Haematology Consultant Haematologist Derriford Hospital and Peninsula Medical School Plymouth DISCLOSURES OF COMMERCIAL SUPPORT Name of Company Research support. Lymphoma is divided into two major categories Hodgkin lymphoma HL and nonHodgkin lymphoma NHL Mantle cell lymphoma MCL is one of about 70 di64256erent subtypes of NHL Lymphoma may arise in any one of three types of lymphocytes B lymphocytes B cells Agents . for . Indolent . L. ymphoma . and . Mantle Cell Lymphoma. . Stephen Ansell, MD, PhD. Mayo Clinic. Tiacci. et al, Nature . Reviews Cancer 6, 437-. 448, 2006.. Would we expect mantle cell lymphoma and follicular lymphoma to respond to similar agents?. Answer: No. Peter Martin, M.D.. The Charles, Lillian and Betty . Neuwirth. Clinical Scholar in . Oncology. Assistant Professor of Medicine. Let’s define “eligible”. N=1066. Abrahamsson. A et al. Blood 2014;124:1288-1295. Common (West), low-grade B-cell lymphoma. Affects elderly. Arises from germinal center B-cell. Lymphoma cells have specific translocation t(14:18), in which Bcl2 gene on chr18 fuses with . IgH. gene on chr14, causing . actual. . video-recorded proceedings from the . live . CME event and may include the use of trade names and other raw, unedited content. . Moderator. Neil Love, MD. Faculty . Dissecting the Decision: . Zahra Mozaheb MD. Assistant professor of Hematology-Oncology . Mashhad University of Medical Science. Iran Mashhad. “5th world Hematologists congress" . Lymphoid malignancies are remarkable and. . Non-Hodgkin’s lymphoma (. NHL) is a term covering all . lymphoproliferative. system malignancies except Hodgkin's lymphoma . The disease is rare in subject under 30 years of age and incidence increase with age . Around two-thirds of all cases are diagnosed in people over 60 years . . Dr. Stefan K. Barta. University of Pennsylvania, USA. July 2020 . 2. Please note: . The views expressed within this presentation are the personal opinions of the author. They do not necessarily represent the views of the authors’ academic institutions or the rest of the LYMPHOMA CONNECT group.. Jarrod Troy ISU-CVM Class of 2014. 416 Billy Sunday Rd Apt. 101. Ames IA 50010. Mentor: . Stephanie Caston, DVM, DACVS-LA. Iowa State University Equine Surgery Service. Case Previously Presented by R David Whitley, DVM, MS, DACVO. MODERATOR : DR. GANAPULE . Definition . Lymphomas are malignant . tumours. of lymphoid tissue which give rise to solid tissue masses.. Heterogenous. group of disorders.. HODGKINS LYMPHOMA. NON-HODGKINS. Helpline: 800 500 9976 | helpline@lymphoma.org Understanding LymphomaDiffuse Large B-Cell Lymphoma: Relapsed/Refractory Diffuse large B-cell lymphoma (DLBCL) is the most common form of non-Hodgkin l DiagnosisThe diagnosis of lymphoma is many times straightforward. Definitive diagnosis can be obtained by either cytologic or histopathologic evaluationof the affected organ system. Because multicent Overview Case 3 • 59 year old man with lymphadenopathy in the neck, supraclavicular area, inguinal area . He states that he has had LN for at least 18 months and they have waxed and waned . Prof. . Alexey V. Danilov, MD, PhD,. 1. Dr. Massimo . Magagnoli. , MD,. 2 . Dr. Matthew J. . Matasar. , MD. 3. . SELECTED HIGHLIGHTS. 1. City of Hope National Medical Center, Duarte, CA, USA; . 2. Humanitas Cancer Center, .