PPT-Study Designs in GWAS

Jess Paulus ScD January 30 2013 Todays topics Casecontrol studies Population based Hospital based Nested studies Selection bias Introduction to population stratification. His philosophy is simple: it only takes a little longer to do it right. But it took 15 years of training  and exposure to decking business to engrave that attitude upon his everyday approach to every project . After years of working for one of the tri-state areas top deck builders, he set out to start a company on his own set of standards. Applications in Plant Breeding. Jennifer Kling. Oregon State University. Outline – Augmented Designs. Essential features. When are they used in plant breeding?. Design options. Today - one-way . control of . IGSS 2015 Tutorial. Ben . Domingue. Gameplan. Overview. What are polygenic scores?. How are they used?. How are they created?. You create them.. Top hits. Homebrewed Genome-wide. PRSice. . Caveats, etc.. Jeff Barrett. Challenges to GWAS?. Data quality control . No common, single SNP main effects (all epistasis or rare variants or …). Sample size too small to detect effects. Computational . burden. Multiple . Colorado School of Public Health. January 30. th. , 2013. Table of Contents. Orientation. Introduction. Components of a Phase I Trial. Phase I Trial Designs. Rule-Based Designs. Statistical Designs. References. Arrow Attachment . Designs (2 PCBs). Arrow Attachment . Designs (1 PCB). via . Mining . GWAS S. tatistics . Yue. Wang, . Xintao. Wu and . Xinghua Shi. College of Computing and Informatics, . University of North Carolina at Charlotte . Background. Data . privacy in genome-wide association studies (GWAS) is . for Colorectal . Cancer. Ulrike (. Riki. ) Peters. Fred Hutchinson Cancer Research Center. University of Washington. Overview. Significance and rationale. . Current efforts on rare and less frequent variants. Amazing Cupcake Designs . Types of Icings . Buttercream Icing . 185g butter, softened. 2 1/4 cups icing sugar mixture. 2 tablespoons milk. Method. Using an electric mixer, beat butter in a bowl until pale. Gradually add icing sugar mixture and milk, beating constantly until combined.. IV External Validity Hardy-Weinberg equilibrium. Meta-analysis. SNP Imputation. Review what we have learned about the genetics of common disease from GWAS. Where do we go from here? What do we go with GWAS results.. functional characterization of GWAS loci. Wood is still one of the most popular materials around. And it’s easy to see why – wood has a natural warmth and beauty that can give any space a feeling of comfort and elegance. If you’re looking for a new wooden bed for your bedroom, check out these 8 Wooden Bed Designs that will give your space a modern appeal. Inês Barroso. Joint Head of Human Genetics. Metabolic Disease Group Leader. Wellcome. Trust Sanger Institute. 1. Objectives. Why perform meta-analysis?. How? . What are the issues to consider?. What can you gain?. Clinical Immunology. March 26, 2013. HARVARD. MEDICAL SCHOOL. Overview. Clinical characteristics and pathophysiology. Differential diagnosis. Exam and laboratory studies. Treatment strategy. Research opportunities.