PPT-Genetic Variation I:

MUTATION The genetic substrate for natural selection AND the Raw Material for Evolution Dr Carol E Lee University of Wisconsin 1 Reduction of Variation Genetic Drift Inbreeding . HapMap. Peter Castaldi. January 29, 2013. Objectives. Introduce the concept of linkage disequilibrium (LD). Describe how the . HapMap. project provides publically available information on genetic variation and LD structure. How to conserve and manage specific species populations. Jenny J. Warnken. Global Biodiversity. *The variety of living . organisms. and the variety of . processes. t. hat . support. these organisms* . Ling Fung . Tang. 1,5. , . Michael L . Heuer. *2. , Nathan Salomonis. 3. , Alexander Pico. 4. , . Pui. Yan Kwok. 1,5,6. University . of California, San Francisco, Institute of Human Genetics, San Francisco, CA, . B. razil. W. el. l. . li. t. an. d . low-nu. t. rient . habitat. Stic. k. y. . underg. r. ound leaves. Eat. s . worms!. P. ereir. a. e. t. . al. . 2012. Th. e. . Pl. a. n. t. o. f. th. e. . D. Population structure . in case-control studies. Population consists of underlying subpopulations.. Disease prevalence different between subpopulations.. Cases preferentially ascertained from specific subpopulations.. Dept. Veterinary Integrated Biosciences. College of Veterinary Medicine and Biomedical Science. Texas A&M University. Genetic Testing of Feral Horses. Testing began in early 1990s.. Usually at the request of an individual from a specific HMA or a private individual.. Asexual Reproduction. only one parent is involved.. 100% of the genetic material from the one parent is passed on.. Bacteria . primarily reproduce asexually.. Examples of Asexual Reproduction. Binary fission . Image from about.com . meiosis_metaphase_1.jpg. . Mutations. (changes in an organism’s DNA) are the . original. . source of . all. genetic variation. Mutations create different versions of genes called . eyes, what . frequency of the population . is hybrid for brown eyes? Homozygous for brown eyes. ?. 2. . How . does sexual . reproduction . produce variation. ?. 3. Why are point/substitution mutations also known as silent mutations?. Your Subtitle Goes Here. Introduction. Two objectives:. Major concepts related to human genetic variation.. Relationship between basic biomedical research and the improvement of personal and public health.. You can compare dogs of every breed imaginable! . There is an enormous range of characteristics that are the result of . genetic variation. . . The differences among breeds of dogs are so great that someone might think that many of these breeds are different species. . y = . kx. , where k ≠ 0. . The constant of variation for a direct variation . k. is the coefficient of . x.. Example of direct variation. : The time it takes to hear thunder varies directly with the distance from lightning. (As the distance from lightning increases, so does the time it takes you to hear the thunder!). By exploring the characteristics offspring inherit when living things reproduce, I can distinguish between inherited and non-inherited characteristics.. SCN 2-14b. Learning intentions. Identify some of the differences between people.. Associate Professor. Variation. . Importance of variation. . Types of variation. . Phenotypic variation. Partitioning of phenotypic variation. Causes of phenotypic variation. G. enetic variation.