PPT-Thalassemias أ.م.د.ميسم

مؤيد علو ش Lec 2 Thalassaemias Objectives 1Define thalassemia and its main types β and α 2 Know the genetic lesions of each of β and α thalassemia 3Know the difference between thalassemia minor and major. University of Medicine 1. Disorders of Red Blood Cells. 1. Functions of RBCs. O. 2. transport (Hb in the RBCs). CO. 2. transport. Acid-base balance. 2. Functional Importance of the Biconcave Shape of RBCs. : are genetic(AR) disorders in . globin. chain production. . In individuals with β. -thalassemia. , there is either: . complete. absence of β-globin gene production . (β. 0. -thalassemia). By Louann W. Lawrence, Larry A. Broussard . Introduction. Porphyrins, hemoglobin, & myoglobin all contain porphyrin ring: 4 pyrrole groups bonded by methene bridges.. Porphyrins can chelate metals . THALASSEMIA SYNDROMES Info Sheet 1800ROSWELL (1  8007679355) | RoswellPark.org UNDERSTANDING HEMOGLOBIN This important protein in your red blood cells carries oxygen مؤيد علوش. Introduction. THE HAEMOGLOBIN MOLECULE. Human . haemoglobin. is formed from two pairs of . globin chains . each with a . haem. . group attached.. Seven . different globin . chains are . Case 2013-4. Melike. . Pekmezci. , MD. Arie. Perry, MD. Conflict of interest. None to disclose. Clinical . H. istory. 68-year-old . woman . Missionary . with recent travel history to . Ghana. Ocular toxoplasmosis- on Bactrim. . Assist. Prof. . Dr.Maysem. . Mouayad. . Alwash. . Note:. The . thalassaemias. are classified into . α. -, . β. -, . δβ. -, . γδβ. -, . δ. -, . γ. - and . εγδβ. -thalassaemias, according to the type of globin chain(s).