Yvonne Lin AP Bio 2 aka Phages Bacterial VIRUS Attacks infects and replicates within bacteria Discovered by Frederick Twort Great Britain 1915 Species specific named after the group or species it infects ID: 220107
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Slide1
Bacteriophage
Yvonne
Lin
AP
Bio
2Slide2
a.k.a. Phages
Bacterial
VIRUS
Attacks, infects, and replicates within bacteriaDiscovered by Frederick Twort (Great Britain, 1915)Species specific – named after the group or species it infectsSlide3
Structure of Bacteriophage
Can be simple or complex
Size and
shape varyBasic features – capsid (head) + tailCapsid – made up of proteins that protect DNA or RNATail – hollow tube, nucleic acid passes through to infect host cellSlide4
Lysogenic CycleSlide5
Lytic CycleSlide6
Applications
Phage therapy – treat bacterial infections that are resistant to antibiotics by destroying them
Phage typing – identify pathogenic bacteria
Kill specific bacteria found in food (eg. Cheese)Slide7
Lambda phage
Enterobacteria
phage
λ (coliphage λ)Infects bacteria Escherichia coli (E. coli)Most studied in genetic researchesUsed as a vector for the cloning of recombinant DNASlide8
Thank you for listening
Sources:
http://textbookofbacteriology.net/
phage.htmlhttp://phages.org/bacteriophage/http://www.cellsalive.com/phage.htm