PPT-21 The Immune System: Innate and Adaptive:Body Defenses: Part A

Ligand In biochemistry and pharmacology a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose In proteinligand binding the ligand is usually a molecule which produces a signal by binding to a site on a target protein The binding typically results in a change of conformation of the target protein. non-AIDS Morbidity. Peter W. Hunt, MD. Associate Professor of Medicine. UCSF HIV/AIDS Division. A shift in focus…. T cell activation as a target for interventions in the pre-ART era. Monocyte activation and inflammation a target during treated HIV disease. A. The body has two main mechanisms of defenses. 1. Innate defense mechanisms – first line of defense. A) These defenses are non-specific and . inherited. Immunity Overview. B) Examples:. 1. ) Physical barriers. Chapter 16: Innate (nonspecific) Immunity. Some terms:. Susceptibility. : Lack of immunity to a disease.. Immunity. : Ability to ward off disease.. . . immunity. : Defenses against any pathogen.. Chaparral High School. What is immunology?. Very simply, it is the study of our body’s defense against infection and disease.. Even though we are constantly bombarded by microorganisms, we rarely become sick. Why?. Cells of the Immune System. Physical & Chemical Barriers. Innate and Adaptive Immunity. Innate Defenses. Nonspecific physical and chemical barriers that contribute to resistance against infection. Learning objectives. By the end of this session student will be able to. . Define innate immunity, acquired immunity. . To understand cells involved in . innate . and acquired . immunity. IMMUNITY. By . Dr. Sunita Mittal. Learning Objectives. To understand about acquired or adaptive immunity. Steps of humoral immune response. Steps of cellular immune response. Cytokines. Unwanted effects of immune system. Maria Bleier . PATH 417. Overview. The Case. 10 . yr. old male patient . Ronnie McDonald.. Developed abdominal cramps, bloody diarrhea and low grade fever. Physician’s examination: . Asks about history in terms of food consumed – undercooked hamburgers from previous weekend as prime suspect. The Immune System. The immune system is a group of cells & soluble molecules, which interact & distinguish patterns in the body as “self” or “non-self,” in order to eliminate those that are “non-self.”. Abbas. University of California San Francisco. FOCiS. Lecture outline. Components of innate immunity. Recognition of microbes and dead cells . Toll Like Receptors. NOD . Like Receptors/. Inflammasome. Dr. . M.A.Thomas. . FUNCTIONS . OF THE IMMUNE SYSTEM. :. Recognize. , destroy and clear a diversity of pathogens. .. Initiate . tissue and wound healing processes. .. Recognize . and clear damaged self components. innate immunity. Prof dr. . Ihsan. . Edan. . Alsaimary. department of microbiology – college of medicine – university of . basrah. Mobile : 07801410838 - . e.mail. : ihsanalsaimary@gmail.com. catherine. . hartnett. The Immune System. Concept 43.1- In innate immunity, recognition and response rely on shared traits of pathogens. Introductory Video. http://www.cleanvideosearch.com/media/action/yt/watch?v=Nw27_jMWw10. There are lots of . micoorganisms. that we . encounter everyday . through breathing, touching, and eating. . Most are detected and . destroyed within minutes or hours . by defense mechanisms that do not rely on the clonal expansion of antigen-specific lymhphocytes. .