PPT-Cholesterol-Lowering Drugs

Victor Nadler Objectives By the end of this class students will be able to Explain the role of dietary lipids and endogenous lipoproteins including dietary cholesterol chylomicrons VLDLC LDLC and . AANUIIOU WELL ALANEIELOWINAUAE fats trans fats and cholesterol that includes a VAIEYOUI VEGEALEANA EEANLOW A dairy products AOILYWIEPEWEE OOELEANUOMEA IMALLVIILEAANOW AWAYEAAOOOUOEMEAEMOVEE skin from poultry 3UIUEMEALEOLOW MEAMAINIEO regular entrees Cholesterol lowering ( HM G - Co A ) inflammatory (p MAPK ) MAPK) Learning outcome. Most cholesterol is synthesised by the liver from saturated fats in the diet. Cholesterol is a component of cell membranes and a precursor for steroid synthesis. High-density lipoprotein (HDL) transports excess cholesterol from the body cells to the liver for elimination. This prevents accumulation of cholesterol in the blood. Low-density lipoprotein (LDL) transports cholesterol to body cells. Most cells have LDL receptors that take LDL into the cell where it releases cholesterol. Once a cell has sufficient cholesterol a negative feedback system inhibits the synthesis of new LDL receptors and LDL circulates in the blood where it may deposit cholesterol in the arteries forming atheromas. A higher ratio of HDL to LDL will result in lower blood cholesterol and a reduced chance of atherosclerosis. . . 1.3 Drugs. Summary of Specification content. Testing of new drugs and clinical trials.. Thalidomide. Learning Outcomes. Define the term ‘drug’.. Give examples of medical drugs.. Explain . why drugs need to be tested before they can be prescribed.. Lowering Sodium without Losi ng Flavor Union Public Schools Tulsa, Oklahoma Lisa Griffin, RD, LD Callie Fowler- Farish Director of Child Nutrition District Executive Chef Union Public Schools-Tulsa, OK Cholesterol is an essential lipid constituent of cell membranes. Cholesterol is a precursor of steroid hormones and of bile acids. Intermediates of cholesterol biosynthesis are required to make vitamin D and for posttranslational modification of membrane proteins. Brian A. . Ference. MD, . MPhil. , . MSc. , John J. P. Kastelein MD, PhD, . Kausik. K. Ray MD, . MPhil. , Henry N. Ginsberg MD, M. John Chapman PhD, . DSc. , Chris J. Packard . DSc. , Ulrich . Laufs. . 4. th. Stage . Dr. Dalia . Abd. Al- Kader. PhD Pharmacology. Coronary heart disease . (CHD) . is correlated with elevated levels of low-density lipoprotein cholesterol (LDL-C; “bad” cholesterol) and triglycerides and low levels of high-density lipoprotein cholesterol (HDL-C; “good cholesterol”). . Functions of Cholesterol. . a precursor of. steroid hormones. (progesterone, testosterone, . estradiol. , cortisol, etc.) . a precursor of. bile acids. . a precursor of . vitamin . D. important component of many mammalian . By. Dr. . Sasan. . Zaeri. PharmD. , PhD. Introduction. Cholesterol. Serves as a component of cell membranes and intracellular organelle membranes. Is involved in the synthesis of certain hormones including estrogen, progesterone, testosterone, adrenal corticosteroids. Check. Change. Control. ® Cholesterol WHAT ARE CHOLESTEROL-LOWERING MEDICATIONS? AMBEN® Cardiovascular If your doctor has decided that you need to take medicine Most heart disease and Gary E. Foresman, MD. January 2019. What Is Middle Path Medicine?. Gary E. Foresman, M.D.. : Board Certified Internal Medicine Physician, Board Certified Functional, Anti-Aging & Regenerative Medicine, Fellow Integrative Cancer Therapies, Founder and President of Middle Path Medicine . Pharmacology Department. 24 SLIDES. 1. Learning objectives. Clinical significance of hyperlipidemia. Management of hyperlipidemia. Drugs used in hyperlipidemia. 2. 2. Two main types of Lipids are triglycerides and cholesterol. Cardioprotective. Effects of . -3 Fatty. Acids. Saraswathi. . Viswanathan. , Ph.D.. Assistant Professor. Department of Internal Medicine/DEM. University of Nebraska Medical Center-Omaha. Abdominal obesity.