PPT-Materials Genome Initiative:

Author : sherrill-nordquist | Published Date : 2016-02-28

Grand Challenges Summit CATALYSTS Breakout Chairs Mark Barteau U Michigan Cathy Tway The Dow Chemical Company Breakout Speakers Plenary 1 Laura Gagliardi

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Materials Genome Initiative:: Transcript

Grand Challenges Summit CATALYSTS Breakout Chairs Mark Barteau U Michigan Cathy Tway The Dow Chemical Company Breakout Speakers Plenary 1 Laura Gagliardi U Minnesota. Denovo genome Denovo genome outline outline novogenome from contigs from assembled contigs annotation Denovo genome Denovo genome Reads contig Gene Gene Annotation Gene Annotation Forgene Jeroen. . Raes. , Jan O . Korbel. , Martin J . Lercher. , Christian von . Mering. and Peer Bork. Presented by Daehwan Kim. Outline. Genome size. Genome sizes of Archaea, Bacteria, and Eukaryotes. Factors affecting genome and genome sizes . Shai. Carmi. Pe’er. lab, Columbia University. and. The Ashkenazi Genome Consortium (TAGC). Boston. September 2013. Outline. Ashkenazi Jewish (AJ) Genetics . and TAGC. Basic Variant Statistics. Utility in AJ Medical . BCB 660. October 20, 2011. From Carson Holt. Annotations. Automated. Ab. initio. (based on genomic sequence alone). Involves comparisons to known proteins (BLAST similarity). Sequence motifs such as start/stop . By Kevin Chen, . Lior. . Pachter. PLoS. Computational Biology, 2005. David Kelley. State of . metagenomics. In July 2005, 9 projects had been completed.. General challenges were becoming apparent. Paper focuses on computational problems. 2. Some genomics history. 1995: first bacterial genome, . Haemophilus influenza. , 1.8 Mbp, sequenced at TIGR. first use of whole-genome shotgun for a bacterium. Fleischmann et al. 1995 became most-cited paper of the year (>3000 citations). Basic Biology: DNA. Genetic information is stored in . deoxyribonucleic acid (DNA) . molecules.. A single DNA molecule is a sequence of . nucleotides. adenine (. A. ). cytosine (. C. ). guanine (. G. Genome sequencing. Next Gen sequencing. Genomics = resources. genome maps. genome sequences. genome clones. DNA microarrays. whole gene collections. functional genomics!. 1980- 1998. 1977- 2003. DNA mapping. Active Roles in Evolution of . Immunity and Pregnancy . Retroviruses 2015. Chicago, June 8, 2015. James A. Shapiro. University of . Chicago. jsha@uchicago.edu. www.shapiro.bsd.uchicago.edu. . Evolutionary time: Genome writing . Fyodor D. Urnov, PhD. Project Leader and Senior Scientist, Sangamo BioSciences, Inc.. NAS International . Summit on Human Gene . Editing. December 3, 2015. Genome Editing . Is. In the Clinic. Fyodor D. Urnov, PhD. . John Glass. for members of the . Venter Institute Synthetic Genomics Group. The J. Craig Venter Institute, . Rockville, MD and San Diego, CA. Construction of a Bacterial Cell Containing Only Essential Genes Necessary to Impart . Timetable for today. Time. Activity. 00:00. Introduction to the session. 00:10. Story cards . 00:20. Info cards. 00:30. Issue cards. 00:40. Discuss two key. issues. 00:45. Feedback your issues. What is DNA?. Nikos. . Kyrpides. Genome . Biology . Program (GBP). DOE Joint Genome institute. IMG. Genes. Genomes. Functions. Metadata. Clusters. SNPs. Proteomics. Regulons. Transcriptomes. IMG Systems Data Types. G-OnRamp Beta Users Workshop. Wilson Leung. 07/2016. Outline. Obtain genome assemblies from NCBI. Transfer . large genomics datasets to Galaxy. Common bioinformatics file formats . D. atatypes in Galaxy.

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