Immune profiling of antigen—specific B cell

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Immune profiling of antigenspecific B cell responses to HIV vaccine immunogens in HVTN clinical trials Pre-conference: Advancing HIV prevention science and access K. Rachael Parks, Fred Hutch, Seattle WA lineage based, germline targeting,

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Immune profiling of antigen—specific B cell responses to HIV vaccine immunogens in HVTN clinical trials Pre-conference: Advancing HIV prevention science and access K. Rachael Parks, Fred Hutch, Seattle WA<br>
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lineage based, germline targeting, trimer-based immunogen design strategies Phase I HVTN clinical trials evaluate HIV Env based immunogens aiming to induce broadly neutralizing antibodies<br>
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lineage based, germline targeting, trimer-based immunogen design strategies
BnAbs have conserved genetic features which serve as a “biomarker” for clinical trial endpoints Antigen binding region Phase I HVTN clinical trials evaluate HIV Env based immunogens aiming to induce broadly neutralizing antibodies<br>