PPT-Extra chromosomal Agents

Transposable elements Mobile genetic elements are segments of DNA able to move from site to site in the genome or between genomes in the same cell Found in both prokaryotes and eukaryotes. Abnormalities in Chromosomal Number. Abnormalities in Chromosomal Structure:. Rearrangements. Fragile Sites. Define:. nondisjunction. polyploidy. aneupoidy. trisomy. monosomy. Abnormalities in chromosomal number. Mutations. Hollywood’s images of . mutation. Mutations. Actual Mutations . in fruit flies. What is a mutation?. A mutation is any change in a cell’s DNA. A mutation can occur in an individual gene. Istanbul. . International. . Hospital. IVF . Center. Is . aneuploidy. . screening. an . efficient. . tool. in . embryo. . selection. ?. Best. . embryo. Symmetrical. . PNs. . with. . equal. Cytogenetics. CDC’s 2003 Science Ambassador Program. Overview. I. Chromosomal Variations. A. Polyploidy. B. Aneuploidy. II. Syndromes resulting from Aneuploidy. A. Trisomy 13. B. Trisomy 18. C. Down Syndrome. — Lecture II. Dr. Steven J. Pittler. VH 375B. Office 4-6744. Cell 612-9720. Suggested Reading: Lewis . 2nd . Edition. Chapter . on . Chromosomes. Chromosomes. Structures that consists primarily of DNA and proteins that are duplicated and transmitted during mitosis or meiosis. Karyotype. Human Chromosomes. Humans have . 46 . chromosomes arranged in . 23. pairs. Two . sex chromosomes. - determine an individual’s sex. Females . have two copies of the large X chromosome. Males have one X and a smaller Y chromosome. Yuvaraja’s College. University of Mysore, Mysore. 11 September 2020. 1. www.hbmahesh.weebly.com. Chromosomes . have definite . structure and organization, which is normally constant from one cell division to next. . 12.1 Chromosomal Inheritance . 1. Genes are located on chromosomes; this is called the . chromosome theory of inheritance. .. 12.1 Chromosomal Inheritance. Chromosomes can be categorized as two types:. 1. A. Background. . 1. Genetics. . 1860’s—. Mendel. . proposed that discrete . inherited . factors . segregate . and assort . independently . during gamete . formation. . 2. Cytology. . . sami. FICOG. CABCOG. Recurrent miscarriage. Definition :. ≥ 3 consecutive losses of clinically recognized pregnancies < 20 week gestation. Ectopic, molar, and biochemical pregnancies not included. What if it’s NOT just the number?. Gene Mutations. Damaged Chromosomes . –. sometimes a portion of a gene or chromosome is lost or damaged during meiosis. Gene mutation. – a mutation that affects the gene. R. Selvi a , Govind Raghav Saranya a , Jyotsna Murthy b , Andrea Mary F a , Solomon F. D. Paul a CORRESPONDING AUTHOR : Ms. R. SELVI Lecturer, Department of Human Genetics, Sri Ramachandra Universit 1 1 . No. 3 . pp: 201 - 208 , March 201 3 Original a rticle The study of chromosomal abnormalities and heteromorphism in couples with 2 or 3 recurrent abortions in Shahid Beheshti H ospital of Ham Prepared by Rania Naoufal, M.D.. Learning Objectives. Chromosome structure. Chromatin. Chromatin exists in several alternative configurations, depending on what that particular stretch of DNA is doing.